wtorek, 10 września 2013

EDS a szpik

"Osteopetrosis congenita is a rare congenital disorder. Itoccurs because of defect in osteoclasts, which are necessary for the formation of bone marrow. As the osteoclasts don’t work correctly, the cavity for bone marrow does not form. Few blood cells form because of absence of bone marrow. Other blood-forming organs, particularly the spleen and liver, take over blood production and become greatly enlarged. Failure of normal osteoclastic bone resorption results in dense, deformed sclerotic bones [1] that show typical and diagnostic patterns on radiograph. Bones look solid on radiograph, but are actually brittle".

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